1. Basic Information:
Product Name Benzocaine
Synonym Aethoform, Anesthesin, Anbesol, Cepacol, Lanacane
CAS 94-09-7
MF C9H11NO2
MW 165.19
EINECS 202-303-5
Assay 99%
Quality Standards Enterprise Standard/Pharma Grade
Appearance White powder
Catalog Local Anesthetics
Package 25kg/Drum
Place of Origin China
Brand Name SMQ
Certification ISO9001, ISO14000, KOSHER
MOQ 1kg
Ref. Price USD 18/kg
Packaging Details 25kg/Drum,1kg/Foil bag
Delivery Time 1-2 days
Payment Terms T/T, Western union, Money gram
Supply Ability 50000 T/Month
2. Overview:
Benzocaine is a local anesthetic commonly used as a topical pain reliever or in cough drops. It is the active ingredient in many over-the-counter anesthetic ointments such as products for oral ulcers. It is also combined with antipyrine to form A/B otic drops to relieve ear pain and remove earwax.
3. Mechanism of action:
Pain is caused by the stimulation of free nerve endings. When the nerve endings are stimulated, sodium enters the neuron, causing depolarization of the nerve and subsequent initiation of an action potential. The action potential is propagated down the nerve toward the central nervous system, which interprets this as pain. Benzocaine acts to inhibit the voltage-dependent sodium channels (VDSCs) on the nerve membrane, stopping the propagation of the action potential.
4. Uses:
Benzocaine is indicated to treat a variety of pain-related conditions. It may be used for:
(1) Local anesthesia of oral and pharyngeal mucous membranes (sore throat, cold sores, canker sores, toothache, sore gums, denture irritation).
(2) Otic Pain (earache).
(3) Surgical or procedural local anesthesia.
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