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CAS No:915087-33-1 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,<br />5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-<br />methylbenzamide
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Enzalutamide

  • CAS No.: 915087-33-1
  • Purity: >98%
  • Weight: 464.435953
  • Formula: C21H16F4N4O2S
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:Enzalutamide
  • CAS No: 915087-33-1
  • Weight: 464.435953
  • Formula: C21H16F4N4O2S
  • Density: 1.49

Details

EnzalutamideEnzalutamide (MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM.

IC50 value: 36 nM [1]

Target: androgen-receptor

in vitro: Enzalutamide has greater affinity to AR than Bicalutamide does in a competition assay with 16β-[18F]fluoro-5α-DHT (18-FDHT) in castration-resistant LNCaP/AR cells (AR-overexpressing).

Target:Adrenergic Receptor

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CAS No:915087-33-1 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,<br />5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-<br />methylbenzamide

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