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CAS No:870281-82-6 5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one
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CAL-101

  • CAS No.: 870281-82-6
  • Purity: >98%
  • Weight: 415.423023
  • Formula: C22H18FN7O
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:CAL-101
  • CAS No: 870281-82-6
  • Weight: 415.423023
  • Formula: C22H18FN7O
  • Density: 1.47

Details

CAL-101CAL-101 (Idelalisib, GS-1101) is a selective p110δ inhibitor with IC50 of 2.5 nM; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR.

IC50 value: 2.5 nM [1]

Target: p110δ

in vitro: CAL-101 is not sensitive to other PI3K class I subunits including p110α, p110β, and p110γ.

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CAS No:870281-82-6 5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one

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