Product name:Cabergoline
Synonyms:6-Allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide
Formula:(C6H9NO)n.(C4H6O2)m
Molecular weight:451.60
CAS number:81409-90-7
Appearance :White or almost white crystalline powder
Identification :IR; X-ray; HPLC.
Optical rotation :-77.0o ~ -83.0 o
Loss on drying :NMT 0.50%
Cabergoline Imp A :NMT 0.15%
Allyl amide :NMT 0.10%
Allyl DHLA :NMT 0.15%
Cabergoline oxide :NMT 0.10%
Other individual impurities : NMT 0.10%
Total impurities :NMT 0.50%
Dichloromethane :NMT 100ppm
Acetone :NMT 200ppm
Tert-butyl methyl ether :NMT 200ppm
Xylene :NMT 1500ppm
Heptane :NMT 1000ppm
Residue on ignition :NMT 0.10%
Heavy metals :NMT 20ppm
Particle size :90% of particle size NMT 80 μm
Bulk density :0.20 ~ 0.35g/cm3
Assay (HPLC) :98.0% ~ 102.0%(recalculated on anhydrous basis)
Standard: EP6.0,USP30
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