Healthy Cortical hormone Purity 99% Fluticasone Propionate CAS:80474-14-2

Healthy Cortical hormone Purity 99% Fluticasone Propionate CAS:80474-14-2

Product Details:

1. CAS No: 80474-14-2
2. MF: C27H30Cl2O6
3. MW: 521.43
4. Purity: 99%
5. Package: 1kg/aluminum foil bag
6. Appearance: white crystall powder.

Description:

Fluticasone propionate is a white powder with a molecular weight of 500.6, and the empirical formula is C25H31F3O5S. It is practically insoluble in water, freely soluble in dimethyl sulfoxide and dimethylformamide, and slightly soluble in methanol and 95% ethanol.
FLONASE Nasal Spray, 50 mcg is an aqueous suspension of microfine fluticasone propionate for topical administration to the nasal mucosa by means of a metering, atomizing spray pump. FLONASE Nasal Spray also contains microcrystalline cellulose and carboxymethylcellulose sodium,dextrose, 0.02% w/w benzalkonium chloride, polysorbate 80, and 0.25% w/w phenylethyl alcohol, and has a pH between 5 and 7.
After initial priming, each actuation delivers 50 mcg of fluticasone propionate in 100 mg of formulation through the nasal adapter.


Healthy Cortical hormone Purity 99% Fluticasone Propionate CAS:80474-14-2

Use:

Fluticasone propionate belongs to a class of drugs known as corticosteroids, specifically glucocorticoids, which are hormones that predominantly affect the metabolism of carbohydrates and, to a lesser extent, fat and protein. It is used to treat asthma, allergic rhinitis, nasal polyps, various skin disorders and Crohn's disease and ulcerative colitis. It is also used to treat eosinophilic esophagitis.

Drug Interactions:
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this drug are: HIV protease inhibitors (such as lopinavir, ritonavir).

Specifications :

tems
Specifications
Results
Description
White or almost white powder
Conforms
Identification
IR& HPLC
Conforms
Specific Rotation
+32°~+36°
+33.26°
Related substances
Impurity D, G≤0.3%
Conforms
Impurity A,B,C, E, F, H, I≤0.2%
Conforms
Impurity with RRT 1.23≤0.2%
Conforms
Any other impurity≤0.1%
Conforms
Total impurity≤1.2%
0.75%
Acetone
≤1.0%
Conforms
Water
≤0.2%
0.12%
Assay (by HPLC)
97.0~102%
99.05%
Particle size
90%≤10μm
Conforms
Conclusion
The results conform to EP6

Competitive Advantage:

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Contact Way:

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