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Description: LY2835219 LY2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM, respectively. IC50 Value: 2 nM(CDK4); 10 nM(CDK6) Target: CDK4/6 in vitro: LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor ...
Description: LY2857785 LY2857785 is a potent and selective CDK9 inhibitor; significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines. IC50 value: Tar...