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CAS No:630124-46-8 1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-<br />(methylamino)pyrimidin-4-yl]oxyphenyl]urea
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AST 487

  • CAS No.: 630124-46-8
  • Purity: >98%
  • Weight: 529.55731
  • Formula: C26H30F3N7O2
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:AST 487
  • CAS No: 630124-46-8
  • Weight: 529.55731
  • Formula: C26H30F3N7O2

Details

AST 487AST487(NVP-AST487) is a Ret kinase inhibitor/FLT3 inhibitor with IC50 of 0.88 uM for Ret.

IC50 value: 0.88 uM

Target: Ret/FLT3

AST 487 displays high selectivity and potency toward FLT3 as a molecular target, and which could potentially be used to override drug resistance in AML.

Target:PPAR

Product Links:http://www.medchemexpress.cn/ast-487.html

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CAS No:630124-46-8 1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-<br />(methylamino)pyrimidin-4-yl]oxyphenyl]urea

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