CAS NO.: 595-33-5
EINECS: 209-864-5
Assay: 99%
Molecular Formula:C24H32O4
Molecular Weight:384.51
Quality Standard: EP5/USP34
Packing:5kg/tin,20kg/drum
Appearance: White or light yellow crystalline powder (methanol), odorless and tasteless. Melting point 214-216 ℃. Soluble in acetone, slightly soluble in ethanol, ethyl ether, insoluble in water
Usage:
1. Mainly used for short-acting oral contraceptives, also can be used for intramuscular injection of long-acting contraceptives.
2. For the treatment of dysmenorrhea, amenorrhea, dysfunctional uterine bleeding, endometriosis and endometrial adenocarcinoma
Product Description
Megestrol acetate (INN, USAN, BAN, JAN) (abbreviated as MGA or MA, and sold mainly under the brand names Megace and Megace ES), also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, is a steroidal progestin and progesterone derivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropic effects.
Though sometimes referred to simply as megestrol, it is important to clarify that megestrol acetate is not the same as megestrol, which is a closely related but different compound.
Megestrol acetate has powerful antiandrogenic and antiestrogenic effects in humans at sufficient doses, capable of decreasing circulating androgen and estrogen concentrations to castrate levels in both sexes and significantly lowering the expression of the androgen receptor (AR) and the estrogen receptor (ER) in the body; as an example, one study in men with benign prostatic hyperplasia who were treated with 120-160 mg of megestrol acetate per day for 3 to 11 days found average decreases in AR quantity of 73% and 86% in the cytoplasm and nucleus of prostatic cells, respectively.[12] These actions are likely the result of a strong activation of the PR, which suppresses the secretion of the gonadotropins-peptide hormones responsible for signaling the body to produce not only progesterone but also the androgens and the estrogens-from the pituitary gland as a form of negative feedback inhibition, and hence downregulates the hypothalamic-pituitary-gonadal (HPG) axis, resulting in decreased levels of the sex hormones and their associated enzymes, carriers (e.g., sex hormone-binding globulin), and receptors.It is the antiandrogenic and antiestrogenic effects of megestrol acetate mediated by suppression of the HPG axis that are believed to be largely responsible for its beneficial effects against androgen and estrogen-sensitive cancers, respectively.
Choose our reasons:
Reason1: High quality with competitive price:
1)Standard: Enterprise Standard
2)We are manufacturer and can provide high quality products with factory price.
Reason2: Fast and safe delivery
1)We will send the package within 24 hours after receipt of the payment. Tracking number available
2)Secure and discreet shipment. Transportation depends on your decision.
3)Customs pass rate 99%min.
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
Reason3: We have clients throughout the world.
1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
If you have any questions, you can contact me at any time.
For more infomation,pls sent E-mail to ycgl01@yccreate.com or link in skype :echo01_5
We also provide the following with products:
TESTOSTERONE SERIES
Testosterone base (CAS: 58-22-0)
Testosterone enanthate (CAS: 315-37-7)
Testosterone acetate (CAS: 1045-69-8)
Testosterone propionate (CAS: 57-85-2)
Testosterone cypionate (CAS: 58-20-8)
Testosterone phenylpropionate (CAS: 1255-49-8)
Testosterone isocaproate (CAS: 15262-86-9)
Testosterone decanoate (CAS: 5721-91-5)
Testosterone Sustanon 250
Testosterone undecanoate (CAS: 5949-44-0)
Methyltestosterone (17-Alpha-Methyl-Testosterone) (CAS: 65-04-3)
Methyltestosterone (17-methyltestosterone) (CAS: 58-18-4)
Methyltestosterone (CAS: 1039-17-4)
Turinabol (4-Chlorotestosterone Acetate, Clostebol Acetate) (CAS: 855-19-6)
Oral turinabol (4-Chlorodehydromethyltestosterone) (CAS: 2446-23-3)
Mestanolone (CAS: 521-11-9)
Stanolone (androstanolone) (CAS: 521-18-6)
Mesterolone (Proviron) (CAS: 1424-00-6)
Fluoxymesterone (Halotestin) (CAS: 76-43-7)
Permanent link: http://www.vvchem.com/sell/cas:595-33-5,3321900.html
China
United States 
