Testosterone Undecanoate Raw Testosterone Powder Test Undecanoate For Musclebuilding
Synonyms: testosterone caproate,testosterone caproate;4-Androsten-17beta-ol-3-one Decanoate
CAS: 5949-44-0
EINECS: 227-712-6
Assay: 99% min.
Molecular Formula: C30H48O3
Molecular weight: 456.70
Packing: 1kg/tin
Character: White crystalline powder.
Usage: Male hormone, for male sexual dysfunction, aplastic anemia
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Description:
Andriol is a unique oral testosterone product, developed by the international drug firm Organon. One of the more recently developed anabolic steroids, Andriol first became available in the early 1980′s.
This compound contains 40 mg of testosterone undecanoate, based in oil (oleic acid) and sealed inside a capsule. Subtracting the ester weight, this equates to a dosage of approximately 25mg of raw testosterone per cap. The design of this steroid is quite different from that of most oral steroids. Drugs administered orally generally enter the blood stream through the liver.
When a steroid compound is given this way without some form of structural protection, it will be quickly broken down during the "first pass". This process leaves very little steroid intact, basically deactivating the drug. Adding a methyl group (c-17 AA) to the structure is one way to protect it from this process, however stress is also placed on the liver as a result. In some instances this stress can lead to actual damage to liver tissues, so the designers of this steroid sought another way to protect the testosterone molecule.
With Andriol, this was accomplished by making a form of testosterone that would be absorbed through the lymphatic system. This is due to its high fat solubility brought about by the ester, and its suspension in oil.
Having the compound absorbed this way was thought to be very advantageous, as it allows the steroid to bypass the destructive first-pass through liver. This should permit the compound to enter the blood stream intact, without the need for a harsh chemical alteration. The ester breaks off once it is in circulation of course, yielding free active Pharmacokinetics of Oral Testosterone. In design this steroid appears to be undecanoate that of a completely liver safe and orally active form of testosterone.
On paper this drug seems like a great oral testosterone product. Clean, safe and worlds apart from other oral testosterone derivatives like the crude methyltestosterone. But as we always hear in life, if it looks to good to be true, it probably is. There are definitely some issues with Andriol. The first problem is that bioavailability, although clearly worlds apart from trying to take straight testosterone orally, is probably not significant next to c17alpha alkylated orals.
One might also pay interest to the "mildness" of this compound as described by other bodybuilding materials. Andriol is often spoken about as some type of magic product, which to spite being a form of regular testosterone somehow allows for only minimal estrogen conversion.
Applications:
Athletes typically find that in doses of less than 240mg per day (6 capsules) effects are generally not seen at all. 240mg of testosterone ester daily, the primary male androgen, and only a meager effect. When doses go higher, maybe 8-10 capsules (320-400mg), new muscle growth is slight to moderate at best, but no incredible bulky gains are ever reported.
Logic leads one to believe that only a little testosterone is making its way into circulation. Testosterone is a powerful hormone no matter what the ester or form of administration. If it were active in the blood stream, the results would have to be pronounced. When one injects an oil based testosterone ester like cypionate, a dosage of 400mg per week is more than sufficient to see results. 400mg Andriol per day should be packing on an incredible amount of mass.
Where does it all go? Individual problems with absorption may play a role into things here. Clearly there is little to be said except that this drug is unpredictable in its ability to be absorbed and utilized by the body. While one day you might be getting great absorption, perhaps the next day you are getting very little.
Studies with men were no better than with women, where again this drug was shown to be unpredictably absorbed and utilized with blood levels ranging from 11.5 to 60.1 nmol/L with 80mg twice daily.
A. Testosterone undecanoate or testosterone undecylate is an ester of testosterone which is used for the treatment of male hypogonadism, and is currently under research for use as a male contraceptive, testosterone undecanoate is sold and distributed under the brand names Andriol, understor, nebido, pantestone, restandol.
B. Andriol is a version of the anabolic steroid testosterone undecanoatedeveloped by the pharmaceutical company organon, testosterone is said to enter the body as a fat through the lymphatic system, experience from user indicates that in dose of less than 240mg per day, effects are negligible, except at every onset of use, while even in higher dose , effects are still minimal , testosterone undecanoate is therefor thought that most of the steroid is somehow not making it into the blood stream.
COA:
Test Items Specification Test Results
Appearance White or almost white crystalline powder Conform
Loss on drying ¨Q0.5% 0.24%
Optical rotation +68??~+72?? 70.3??
Melting Point 60~65??C 61-63??C
(HPLC)Assay 97-103.0% 98.71%
Free acid 0.5%max 0.35%
Conclusion The aboye product conforms analysis standard
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