Healthy Athletes Testosterone Propionate Anabolic Steroid Hormones CAS 57-85-2 Muscle Growth
Testosterone propionate
Chemical Name: 4-Androsten-17beta-ol-3-one propionate
CAS NO.: 57-85-2
Molecular Formula: C22H32O3
Molecular weight: 344.49
Standard: USP28/BP2003
Assay:99%
EINECS:200-351-1
Character: White crystalline powder.
Storage: Keep it under seal in cool and dark place
Description:
Testosterone is the male sex hormone responsible for many of the physical and emotional traits of men. It creates the deeper voices, sex drive, aggression and, of coarse, larger muscles in men. Testosterone makes the muscles retain more nitrogen, which in turn makes the muscle synthesize proteins better, producing larger muscles.
Testosterone propionate is a commonly manufactured, oil-based injectable testosterone compound. The propionate ester will slow the rate in which the steroid is released from the injection site, but only for a few days. Testosterone propionate is therefore much faster acting than other testosterone esters such as cypionate or enanthate, and requires a much more frequent dosing schedule, in order to maintain stable blood levels. While cypionate and enanthate are injected on a weekly or bi-weekly basis, propionate is usually injected every second. The propionate ester can be very irritating to the site of injection.
Applications:
Testosterone Propionate enjoyed a great amount of medical uses for various medical treatments shortly after its release. These included: treatment for male androgen deficiency (andropause or hypogonadism), treatment for sexual dysfunction, and treatment for menopause, treatment for chronic dysfunctional uterine bleeding (menorrhagia), treatment for endometriosis, and many additional countless medical applications. Eventually, as with all anabolic steroids, Testosterone Propionate’s approved medical treatments were eventually reduced by the FDA as a result of the increased control over the prescription drug market granted to the FDA by the United States government. Eventually, Testosterone would only be utilized for male patients.
Testosterone Propionate promotes nitrogen retention in the muscle, and the more nitrogen the muscles hold the more protein the muscles store, and the bigger the muscles get. Testosterone Propionate can also increase the levels of another anabolic hormone, IGF-1, in muscle tissue. IGF-1 is alone highly anabolic and can promote muscle growth. It is responsible for much of the anabolic activity of Growth Hormone (GH). IGF-1 is also one of the few hormones positively correlated with both muscle cell hyperplasia and hyperphasia (this means it both creates more muscle fibers as well as bigger fibers). All of this might lead one to speculate that for pure mass, IGF-1, HGH, and Testosterone Propionate would be a very effective combination. Testosterone Propionate also has the amazing ability to increase the activity of satellite cells. These cells play a very active role in repairing damaged muscle. Testosterone also binds to the androgen receptor (A.R.) to promote all of the A.R dependent mechanisms for muscle gain and fat loss.
Side effects of Testosterone Propionate (and how to counter them)
Estrogenic side effects of Testosterone:
The primary side effects of Testosterone Propionate surround its ability to aromatize into Estrogen. Testosterone itself possesses a moderate level of Estrogenic activity - it holds a moderate affinity to bind to the aromatase enzyme (the enzyme responsible for the conversion of Testosterone into Estrogen). Because of that, a moderate level of aromatization is expected from Testosterone use. To counter this problem there are two solutions:
Selective Estrogen Receptor Modulators (SERMs) like Tamoxifen Citrate (Nolvadex) or Clomifene (brand names: Androxal, Clomid and Omifin) function by binding to the estrogen receptors - filling them and preventing actual estrogen from binding.
Aromatase Inhibitors (AIs) like Anastrozole (Arimidex) function by inhibiting the aromatase process and even lower the body's own estrogen levels. Aromatise Inhibitors are far more effective than SERMs.
Water Retention:
This side effect stems from increased estrogen levels and is countered by aromatase inhibitors (for example Anastrozole - Arimidex).
Increased blood pressure:
This is a result of water retention. It is countered by aromatase inhibitors.
Gynecomastia (aka Gyno / Bitch tits):
Gynecomastia is the abnormal development of breast tissue in males. Enlargement of the breast tissue is associated with increased estrogen levels. This is countered by Selective Estrogen Receptor Modulators or Aromatase Inhibitors.
Androgenic Side effects of Testosterone:
Testosterone androgenic side effects have more to do with the fact that Testosterone is converted into stronger and more potent androgen Dihydrotestosterone (DHT) by the 5-alpha reductase (5AR) enzyme.
The 5-alpha reductase enzyme is present in large amounts in certain tissues, such as the scalp, prostate, and the skin. When Testosterone reaches these tissues, it undergoes a high rate of reduction into its more potent androgenic metabolite DHT. It is DHT that is responsible for the greater severity of androgenic side effects.
Hair Loss:
This side effect is completely dependent on the individual's genetic predisposition. If there are no bald men in your family, this will not be an issue for you. If male pattern baldness runs in your genes you will lose your hair anyway, but testosterone supplementation might speed up the process. This can be countered to some extent with Finasteride and the use of 2% Nizoral (Ketoconazole) shampoo.
Oily skin:
Oily skin makes the hair more shiny. In other animals, males with more shiny fur are more desirable/healthier looking.
Acne:
Oily skin in turn increases chances of pore clogging and formation of Acne. To some extent this can be countered by the use of Nizoral 2% shampoo, where its active ingredient Ketoconazole acts as a topical DHT blocker in skin and scalp, effectively reducing the probability of androgens triggering male pattern baldness as well as acne breakouts caused by increased oily skin. Acne are usually cleared with the discontinuation of steroids not very long after the discontinuation of the testosterone cycle.
Agression:
Studies have shown clear associations between testosterone and aggression. Roid ragea type of impulse control - tendency to overreact to an event that normally wouldn't set you off.
Shrinkage of testicles:
When external testosterone is supplemented our natural testosterone production is lowered. The testicles stop producing testosterone because there is plenty of it from external sournce. As a result they temporarily shrink. During the testosterone cycle there isn't much we can do about testicular atrophy. Once the use of external testosterone comes to an end the natural testosterone production is gradually restored and testicles return to their full size. Steroid users speed up recovery by taking Clomiphene citrate (brand names: Androxal, Clomid and Omifin). HCG (Human chorionic Gonadotropin) is also used to rapidly restore natural testosterone production.
Decreased Libido:
While supplementing with Testosterone, men often notice a hightened libido (sex drive). Likewise they notice a decrease of libido during the period when testosterone supplementation has ended and before natural testosterone production is restarted again (with clomiphene citrate or HCG). ?
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