praziquantel

1. Quick Detail:

Product Name: praziquantel
Synonyms: Drontal; Drontal Plus; Vercom; 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one; 4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-; 5-24-03-00361 (Beilstein Handbook Reference); BRN 0761557; Biltricide
CAS: 55268-74-1
EINECS: 259-559-6
MF: C19H24N2O2
MW: 312.41
Assay: 99%
Appearance: White powder



2. Descriptions:

Praziquantel, marketed as Biltricide, is an anthelmintic used in humans and animals for the treatment of tapeworms and flukes. Specifically, it is effective against schistosoma, Clonorchis sinensis the fish tapeworm Diphyllobothrium latum.

It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
Praziquantel is used to treat diseases in humans, mammals, and fish that are caused by infection with several types of internal/gastrointestinal, and external parasites, including:

Salmon poisoning disease
Hydatid disease caused by infection of various organs with larval stages of tapeworms of the genus Echinococcus
Cysticercosis caused by infection of the brain and/or muscles with the eggs and larvae of the pork tapeworm Taenia solium (though it has been judged less effective than albendazole in treatment of neurocysticercosis)
Feline taeniasis caused in cats by gastrointestinal infection with adult tapeworms of the species Taenia taeniaeformis; used either alone or in combination with pyrantel pamoate
Toxocariasis in cats and dogs whose gut is infected with the roundworms/nematodes Toxocara cati or Toxocara canis, respectively; use is often combined with pyrantel
Schistosomiasis caused by trematodes of the genus Schistosoma. As of 2005, praziquantel is the primary treatment for human schistosomiasis, for which it is usually effective in a single dose.
Clonorchiasis brought on by the Chinese liver fluke Clonorchis sinensis
Paragonimiasis caused by infection with lung flukes, mostly of the species Paragonimus westermani[citation needed]
Fasciolopsiasis caused by intestinal fluke Fasciolopsis buski
Diplozoon paradoxum and other Trematoda infections of many fish species

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