Prednisolone Acetate
Synonyms: (11beta)-21-(Acetyloxy)-11,17-dihydroxypregna-1
CAS: 52-21-1
Molecular formula: C23H30O6
MW: C23H30O6
Packing: 5KG/TIN,2TIN/CTN
Unit: KG
Quality Standards: USP
Chemical Properties: white crystalline powder
Usage: Synthetic corticosteroid; metabolically interconvertible with prednisone.
EINECS:204-726-0
Density:1.28 g/cm3
Boiling Point:582 °C at 760 mmHg
Flash Point:200.2 °C
Assay:98%
Product description:
Prednisolone is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions. It is the active metabolite of the drug prednisone[1] and is used especially in patients with hepatic failure, as these individuals are unable to metabolise prednisone into prednisolone.
Prednisolone is a corticosteroid drug with predominant glucocorticoid and low mineralocorticoid activity, making it useful for the treatment of a wide range of inflammatory and auto-immune conditions such as asthma, uveitis, pyoderma gangrenosum, rheumatoid arthritis, ulcerative colitis, pericarditis, temporal arteritis and Crohn's disease, Bell's palsy, multiple sclerosis, cluster headaches, vasculitis, acute lymphoblastic leukemia and autoimmune hepatitis, systemic lupus erythematosus, Kawasaki disease and dermatomyositis. It is also used for treatment of sarcoidosis, though the mechanism is unknown.
Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile ophthalmic suspension and used to reduce swelling, redness, itching, and allergic reactions affecting the eye.
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