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Clomifene citrate

  • CAS No.: 50-41-9
  • Purity: 98%
  • Min quantity: 10 Kilograms
  • Price: USD 1~1/Kilograms
  • Place of Orign: zhuzhou,Hunan,China
Ms.katharine yan

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Item specifics

  • Product Name.:Clomifene citrate
  • CAS No: 50-41-9
  • Weight: 598.08
  • Formula: C26H28ClNO.C6H8O7
  • Melting Point: 116.5-118°C
  • Boiling Point: 509 °C at 760 mmHg

Details

Clomifene citrate (Clomid)

Another name:2-4-[2-Chloro-1,2-diphenylethenyl]phenoxy-N,N-diethylethanamine citrate
CAS NO: 50-41-9
Purity:99%
Package:25KG/cardboard
Appearance: white or milky white crystalline powder
Structural formula: C26H28ClNO·C6H8O7
Molecular weight: 598.11


Use:
the goods to anti-estrogen fertility inducer, the objects in dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecologic diseases

Clomid is a mixed estrogen agonist/antagonist (activator/blocker) which, when bound to the estrogen receptor, puts it in a somewhat different conformation (shape) than does estradiol. The estrogen receptor requires binding of an estrogen or drug at its binding site and also the binding of any of several cofactors at different sites. Without the binding of the cofactor, the estrogen receptor is inactive. Different tissues use different cofactors. Some of these cofactors are able to bind to the estrogen receptor/Clomid complex, but others are blocked due to the change in shape. The result is that in some tissues Clomid acts as an antagonist - the cofactor used in that tissue cannot bind and so the receptor remains inactive - and in others Clomid acts as an agonist (activator), because the cofactors used in that tissue are able to bind
Clomifene citrate

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