Cortisone acetate
Synonyms:11,20-trione,17,21-dihydroxy-pregn-4-ene-21-acetate;11-dehydro-17-hydroxycorticosterone-21-acetate;11-dehydro-17-hydroxycorticosteroneacetate;17,21-dihydroxypregn-4-ene-3,11,20-trioneacetate;20-trione,21-(acetyloxy)-17-hydroxy-pregn-4-ene-11;21-(acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione;21-acetoxy-17,alpha-hydroxy-3,11,20-triketopregnene-4;21-acetoxy-17,alpha-hydroxypregn-4-ene-3,11,20-trione
CAS:50-04-4
EINECS:200-006-5
MF:C23H30O6
MW:402.48
Melting point 237-240 ° C (lit.)
Refractive index 212 ° (C = 1, MeOH)
Chemical properties of white needle crystal or crystalline powder (acetone), odorless. Stable in air. Mp239-241 ℃, specific rotation [α] 20D +164 ° (0.5%, acetone), [α] 23D +169 ° (chloroform), [α] 25D +208 ° - +217 ° (dioxane) , ethanol solution of the product has an absorption maximum at 240nm wavelength. Soluble in chloroform (1:4), dissolved in acetone (1:75), slightly soluble in ethanol and ether, insoluble in water. This product is dissolved in sulfuric acid without fluorescent yellow (with hydrocortisone acetate phase difference).
Intermediate use of prednisone acetate. Itself as an anti-inflammatory agent. For the treatment of low adrenal function disorders, rheumatoid arthritis, rheumatism, lupus and other diseases.
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