AR-C155858AR-C155858 is a novel inhibitor of the monocarboxylate transporters (MCTs) MCT1 and MCT2 (Ki values are 2.3 and <10 nM respectively); exhibits no activity at MCT4.
IC50 value: 2.3/<10 nM (Ki, MCT1/2) [1] [2]
Target: MCT1/2
in vitro: Co-expression of exogenous embigin was without effect on either the expression of MCT1 or its inhibition by AR-C155858.
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