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CAS No:475207-59-1 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-<br />methylpyridine-2-carboxamide
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Sorafenib (Tosylate)

  • CAS No.: 475207-59-1
  • Purity: >98%
  • Weight: 637.02657
  • Formula: C28H24ClF3N4O6S
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:Sorafenib (Tosylate)
  • CAS No: 475207-59-1
  • Weight: 637.02657
  • Formula: C28H24ClF3N4O6S
  • Boiling Point: 523.3 °C at 760 mmHg
  • Density: 1.454 g/cm3

Details

Sorafenib (Tosylate)Sorafenib tosylate (BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively, BAY 43-9006 suppresses both wild-type and V599E mutant BRAF activity in vitro.

IC50 Value: 6 nM (Raf-1); 22 nM (B-Raf); 90 nM (VEGFR2) [1]

Target: Raf-1

Sorafenib is a drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma) and advanced primary liver cancer (hepatocellular carcinoma).

Target:Raf

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CAS No:475207-59-1 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-<br />methylpyridine-2-carboxamide

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