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CAS No:473727-83-2 2-hydroxy-N,<br />N-dimethyl-3-[[2-[[(1R)-1-(5-methylfuran-2-yl)propyl]amino]-3,<br />4-dioxocyclobuten-1-yl]amino]benzamide
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SCH527123

  • CAS No.: 473727-83-2
  • Purity: >98%
  • Weight: 397.42442
  • Formula: C21H23N3O5
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:SCH527123
  • CAS No: 473727-83-2
  • Weight: 397.42442
  • Formula: C21H23N3O5
  • Melting Point: 118-120℃
  • Boiling Point: 548.67 °C at 760 mmHg
  • Density: 1.34

Details

SCH 527123SCH-527123 is a potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively.

IC50 value: 42 nM (CXCR1); 3 nM (CXCR2) [1]

Target: CXCR1/2

in vitro: Sch527123 inhibits chemokine binding to CXCR1 and CXCR2 receptors in an insurmountable manner and is categorized as an allosteric antagonist.

Target:Survivin

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CAS No:473727-83-2 2-hydroxy-N,<br />N-dimethyl-3-[[2-[[(1R)-1-(5-methylfuran-2-yl)propyl]amino]-3,<br />4-dioxocyclobuten-1-yl]amino]benzamide

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