Ko 143Ko 143 is a potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM), Ko 143 displays > 200-fold selectivity over P-gp and MRP-1 transporters.
IC50 value: 26 nM (EC90) [1]
Target: BCRP
in vitro: Ko143 appears to be the most potent BCRP inhibitor known thus far.
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