Synonym: Ethinyltestosterone,Progestoral
CAS NO: 434-03-7
M.F.: C21H28O2
M.W: 312.45
Packaging: 1kg/tin
Appearance: White or kind of white crystalline powder
Usage: Synthetic progestogen; metabolite of Danazol; intermediate in the synthesis of Spironolactone
Norethisterone is relatively new (it certainly was not available to people in ancient times) and was created in 1951 by chemists working for the pharmaceutical company Syntex in Mexico City. It is a progestin, which is a synthetic version of progestogen which is created naturally in the ovaries and placenta.
Contraindications
1) Medical conditions of you or a family member: are lactose-intolerant; allergic to Norethisterone; jaundice; rashes or itching; severe liver problems or liver tumors; kidney problems; tumors of the breast , womb or ovaries; high levels of fat in the blood; irregular or unusual vaginal bleeding of unknown cause; sickle cell anemia; the rare inherited blood condition called porphyria; heart attack, stroke or angina; a blood clot in the legs or lungs; hypertension; diabetes; depression; migraine; epilepsy; muscle spasms; gallstones; cancer; asthma; elderly; pregnant or breast-feeding; or will be bed-ridden or immobile for a period of time.
2) Medicines Foods and even alcohol are not known to have an adverse effect on its use, but inform your doctor if you are taking and of the following: Aprepitant, Atorvastatin; Phenytoin, Primidone, Ampicillin, Rufinamide; Selegiline; medicines for cancer, medicines for blood pressure, barbiturates, corticosteroids, Rifamycin, Topiramate, Ritonavir, female sex hormones, even the medicinal herb St. John's Wort, or any other medicine, especially anticonvulsants, anti-infectives, tetracyclines, NSAIDs or anything which cause fluid retention, cytotoxics and cytochrome P450 enzyme inducers
Other medicines presenting a concern are those that treat epilepsy (such as phenytoin and carbamazepine); antibiotics to treat an infection (such as rifampicin, co-trimoxazole and the above-mentioned tetracyclines); antiviral medicines to treat HIV (such as ritonavir and nelfinavir); anticancer medicines; medicines for suppressing the immune system (such as cyclosporin); and medicines for Cushing's syndrome (such as aminoglutethimide).
3) Do not take it if you are a smoker. Cigarette smoking increases the risk of blood clotting, and damage to the heart and blood vessels. This is even more pronounced in heavy smoking (15 or more cigarettes each day), and in women who are 35 or more years of age.
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