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Z)-Guggulsterone

  • CAS No.: 39025-23-5
  • Weight: 312.45
  • Formula: C21H28O2
  • Place of Orign: Wuhan,Hubei,China
Ms.Melody Zhang

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Item specifics

  • Product Name.:Z)-Guggulsterone
  • CAS No: 39025-23-5
  • Weight: 312.45
  • Formula: C21H28O2
  • Boiling Point: 463.3°Cat760mmHg
  • Density: 1.1g/cm3

Details

Product Name:(Z)-Guggulsterone
Synonyms:4,17(20)-(CIS)-PREGNADIEN-3,16-DIONE;GUGULSTERONE;GUGGULESTERONE Z;GUGGULSTERONE;GUGGULSTERONE Z;GUGGULSTERONE (Z FORM);CIS-4,17(20)-PREGNADIENE-3,16-DIONE;CIS GUGGULSTERONE
CAS:39025-23-5
MF:C21H28O2
MW:312.45
Usage:Z-Guggulsterone acts as an α-glucosidase inhibitor also known as a hypolipidemic agent.
Biological Activity:Broad spectrum steroid receptor ligand; mineralocorticoid, progesterone and glucocorticoid receptor antagonist (K i values are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (K i = 315 nM). Induces apoptosis in prostate cancer cells and inhibits angiogenesis via suppression of the VEGF-VEGFR2-Akt signalling pathway. Exhibits antilipidemic activity via antagonism of the farnesoid X receptor (FXR) and displays antiseptic, antirheumatic and anti-inflammatory activity in vivo . More active isomer of Guggulsterone (Pregna-4,17(20)-diene-3,16-dione ).
More information, pls contact through 2355935184 at ycphar.com
Z)-Guggulsterone

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