Cinacalcet hydrochloride / N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1- amine

Cinacalcet Hydrochloride

(( R)- -Methyl-N-[3-[3-(trifluoromethyl)phenyl)propyl]-1-napthalenemethanamine Hydrochloride; (R)-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-(1-napthyl)ethylamine) Hydrochloride; Mimpara; Sensipar)

Storage: -20°CShipping: RT

Clinical trial in secondary hyperparathyroidism.

Solubility: Methanol

Melting Point: 170-172oC

Method for Determining Identity:
Proton NMR Spectroscopic Analysis

TLC Conditions:
SiO2; Hexane: Ethyl Acetate: NH4OH; 6:3: 0.1; Visualized with UV and AMCS; Single spot; Rf=0.55

Chloride content: ~9%

Specific Rotation (c=1, Methanol):
-30.8o

Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Toxicity and Hazards:
All products should be handled by qualified personnel only, trained in laboratory procedures.

CAS Number:
364782-34-3

Molecular Formula:
C22H22F3N?HCl

Molecular Weight:
393.87

Source: Synthetic
Purity: ~90%
Form: Supplied as an off-white to pale beige solid.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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