Current position:Home > Selling > Dasatinib
CAS No:302962-49-8 N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-<br />methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
Add to My Favorites

Dasatinib

  • CAS No.: 302962-49-8
  • Purity: >98%
  • Weight: 488.00554
  • Formula: C22H26ClN7O2S
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

Supplier Details

View the Seller's Store
Product Details
Company Profile

Item specifics

  • Product Name.:Dasatinib
  • CAS No: 302962-49-8
  • Weight: 488.00554
  • Formula: C22H26ClN7O2S
  • Melting Point: 275-286°C
  • Boiling Point: °Cat760mmHg
  • Density: 1.408g/cm3

Details

DasatinibDasatinib(BMS-354825) is a potent and dual Abl/ Src inhibitor IC50 of <1 nM/0.8 nM respectively; also inhibit c-Kit (WT)/c-Kit (D816V) with IC50 of 79 nM/37 nM.

IC50 value: <1 nM/0.8 nM(Abl/ Src); 79 nM/37 nM (c-Kit WT/c-Kit D816V) [1] [2]

Target: Abl; Src; c-Kit

in vitro: Dasatinib is more effective than imatinib in inhibiting the proliferation of Ba/F3 cells expressing wild-type Bcr-Abl and Bcr-Abl mutants, with the exception of T315I.

Target:Aurora Kinase

Product Links:http://www.medchemexpress.cn/dasatinib.html

Permanent link:http://www.medchemexpress.com/dasatinib.html

Permanent link:

Send message to this supplier

CAS No:302962-49-8 N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-<br />methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide

- Enter between 20 to 3,000 characters. English only.
Your message must be between 20-2000 characters.English only.

Look for similar items

  • Home > Organic Intermediates > Pharmaceutical Intermediates

    • Related Products