Cutting/Losing Weight Cetilistat Atl-962 CAS 282526-98-1
Additional Info.
Trademark:
Yuancheng saichuang
Packing:
2mg/Vial, 5mg/Vial Cetilistat Atl-962
Standard:
99% Cetilistat ATL-962
Origin:
China Cetilistat Atl-962
Production Capacity:
50kg/Month Cetilistat Atl-962
Product Description
Cetilistat ATL-962 with high quanity and best price for weight reduction and treatment of obesity and Type II diabetes
Basic Info.
Quality: Great
Purity: 99.9%
Export Markets: Global
Additional Info.
Packing: Foil Wrapper
Origin: China
Production Capacity: 500kg/Month
Product Description
Cetilistat (ATL-962)
CAS #: 282526-98-1
Molecular formula: C25H39NO3
Molecular weight: 401.58
Formulation: White powder
Purity: ≥ 99%by HPLC
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Tracking number
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Description:
Cetilistat is a novel inhibitor of pancreatic lipase. The aim of this report is to evaluate the anti-obesity action of cetilistat in diet-induced obesity (DIO) rats. Cetilistat inhibited rat and human pancreatic lipase activity with an IC (50) of 54.8 nmol/l, and 5.95 nmol/l, respectively, meaning that it is 9.2 times more potent for human pancreatic lipase than for that of rat. Cetilistat was orally administered simultaneously with fat emulsion to Sprague-Dawley rats. Plasma triglyceride (TG) concentrations were measured before and after oral fat loading. The elevation in plasma triglyceride concentration by oral fat loading was reduced by cetilistat in a dose-dependent manner at 3, 10, 30, and 100 mg/kg, indicating that cetilistat reduces intestinal fat absorption in rats. Cetilistat was administered to DIO F344 rats as food admixture in a high-fat diet at 4.9, 14.9, or 50.7 mg/kg/day for three weeks. Both triglyceride and nonesterified fatty acid content in the feces were dose-dependently and drastically increased, suggesting the intestinal breakdown of fat and excretion. Body weight (BW) gain and white adipose tissue (WAT) weight were reduced in a dose-dependent manner. In addition, leptin, TG, and total cholesterol (TC) in plasma were reduced and there were no reports of oily stools. These results suggest that cetilistat ameliorates obesity and hyperlipidemia in DIO rats, a plausible animal model of the most common type of human obesity.
English name CAS number content
Metandienone 72-63-9 97-103%
Stanozolol 10418-03-8 98.0-100.5%
Cialis 171596-29-5 ≥99 %
Oxandrolone 53-39-4 97.0-100.5%
Trenbolone acetate 10161-34-9 97-101%
Sildenafil citrate 171599-83-0 98-101%
Ternbolone Enanthate 472-61-546 97.0-101.0%
Chlorhexidine acetate 56-95-1 CP 99%
Oxymetholone 434-07-1 97-103%
Tranexamic acid 1197-18-8 99-101%
Anisic aldehyde 123-11-5 99.50%
17-Methyltestosterone 58-18-4 97%-103%
Dromostanolone propionate 521-12-0 ≥97%
1-Dehydro-4-chloro-17-methyltestosterone 2446-23-3 ≥97%
Methenolone enanthate 303-42-4 ≥98%
Permastril 521-12-0 ≥97%
2-Phenylimidazole 670-96-2 99%
Ketoconazole 65277-42-1 99%
Phenformin hydrochloride 834-28-6 99%
Mesteronlone 1424-00-6 98-102%
Methenolone acetate 434-05-9 97-102%
L-glycine 56-40-6 98.5-101.0%
Stanolone 521-11-9 ≥97%
6-Bronmandrostenedione 38632-00-7 97%
Dehydroepiandrosterone 53-43-0 98%
Dehydroepiandrosterone acetate 853-23-6 98%
Testosterone 58-22-0 98%
Androstenedione 1963-5-8 98%
Testosterone cypionate 58-20-8 98%
Testosterone decanoate 5721-91-5 98%
Drostanolone enanthate
Drostanolone propionate
Testosterone isocaproate 15262-86-9 98%
Testosterone phenylpropionate 1255-49-8 98%
Boldenone undecylenate 13103-34-9 98%
Nandrolone 434-22-0 97%
Nandrolone decanoate 360-70-3 98%
Testosterone enanthate 315-37-7 98%
Testosterone propionate 57-85-2 98%
Boldenone 846-48-0 98%
Testosterone sustanon
Testosterone undecanoate 5949-44-0 98%
Estradiol 50-28-2 98%
Oestradiol 17-heptanoate 4956-37-0 98%
Androstenediol 521-17-5 95%
Estradiol benzoate 50-50-0 98%
Nandrolone phenylpropionate 62-90-8 98%
Testosterone acetate 1045-69-8 98%
Boldenone undecylenate 98%
4-Chlorotestosterone acetate 855-19-6 98%
BOLDENONE CYPIONATE 106505-90-2 98%
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