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Description: T-5224 T-5224 is a selective inhibitor of c-Fos/activator protein (AP)-1, attenuates lipopolysaccharide-induced liver injury in mice. IC50 value: Target: c-Fos/AP1 inhibitor in vitro: T-5224 was converted to its acyl O-glucuronide (G2) by UGT1A1 and ...