Di-tert-butyl dicarbonate is a reagent widely used in organic synthesis.[1] Since this compound can be regarded formally as the acid anhydride derived from a tert-butoxycarbonyl (Boc) group, it is commonly referred to as "Boc anhydride." This pyrocarbonate reacts with amines to give N-tert-butoxycarbonyl or so-called Boc derivatives. These carbamate derivatives do not behave as amines, which allows certain subsequent transformations to occur that would be incompatible with the amine functional group. The Boc group can later be removed from the amine using moderately strong acids (e.g., trifluoroacetic acid). Thus, Boc serves as a protective group, for instance in solid phase peptide synthesis. Boc-protected amines are unreactive to most bases and nucleophiles, allowing for the use of the fluorenylmethyloxycarbonyl group (Fmoc) as an orthogonal protecting group.
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Basic Information
Business Type: Manufacturer
Product/Service (We Buy): 101 - 500 People
Ownership Type: Corporation/Limited Liability Company
Registered Capital: US$2.5 Million - US$5 Million
Year Established: 2013
Number of Employees: 101 - 500 People
Trade & Market
Main Markets: North America,Southeast Asia,Mid East,South America,Eastern Asia,Eastern Europe,Oceania,Western Europe
QA/QC: In House
Number of Production Lines: 7
Number of R&D Staff: 98
Number of QC Staff: 5 - 10 People
Total Annual Sales Volume: US$10 Million - US$50 Million
China
