Hot Selling 99% Purity White Steroid Hormone Powder Dexamethasone Sodium Phosphate
Product Details:?
1,Manufacturer :TOP STEROIDS
2,Molecular Formula:C22H28FNa2O8P
3,Molecular Weight:516.4
4,Purity:99%
5, Character: White Crystalline Powder
6, Synonyms: DEXAMETHASON SODIUM PHOSPHATE;DEXAMETHASONE SODIUM PHOSPHATE;DEXAMETHASONE PHOSPHATE SODIUM;DEXAMETHASONE PHOSPHATE DISODIUM SALT;
Description:
Dexamethasone Sodium Phosphate, a synthetic adrenocortical steroid, is a white or slightly yellow, crystalline powder. It is freely soluble in water and is exceedingly hygroscopic. The molecular weight is 516.41. It is designated chemically as 9-fluoro-11β,17-dihydroxy-16α-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione disodium salt.
Dexamethasone Sodium Phosphate injection, USP is a sterile solution of Dexamethasone Sodium Phosphate, and is supplied in 4 mg/ mL and 10 mg /mL.
Dexamethasone Sodium Phosphate injection, USP 4 mg/mL is a sterile solution for intravenous, intramuscular, intra-articular, intralesional and soft tissue administration. Each mL contains:
Active: Dexamethasone Sodium Phosphate 4.4 mg (equivalent to dexamethasone phosphate 4 mg). Preservatives: Methylparaben 1.5 mg; Propylparaben 0.2 mg. Inactives: Edetate Disodium 0.11 mg; Sodium Citrate Anhydrous 10 mg; Citric Acid and/or Sodium Hydroxide q.s to adjust pH 7.0 to 8.5 and Water for Injection q.s to 1 mL.
Dexamethasone Sodium Phosphate injection, USP 10 mg/mL is a sterile solution for intravenous or intramuscular use only. Each mL contains:
Actives: Dexamethasone Sodium Phosphate 11 mg (equivalent to dexamethasone phosphate 10 mg). Preservatives: Methylparaben 1.5 mg; Propylparaben 0.2 mg. Inactives: Edetate Disodium 0.11 mg; Sodium Citrate Anhydrous 10 mg; Citric Acid and/or Sodium Hydroxide q.s to adjust pH 7.0 to 8.5 and Water for Injection q.s to 1 mL.
Dexamethasone Sodium Phosphate injection has a rapid onset but short duration of action when compared with less soluble preparations. Because of this, it is suitable for the treatment of acute disorders responsive to adrenocortical steroid therapy.
Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs, including dexamethasone, are primarily used for their potent anti-inflammatory effects in disorders of many organ systems.
Glucocorticoids cause profound and varied metabolic effects. In addition, they modify the body's immune responses to diverse stimuli.
At equipotent anti-inflammatory doses, dexamethasone almost completely lacks the sodium-retaining property of hydrocortisone and closely related derivatives of hydrocortisone.
Specifications?:
Analysis Report
Product Dexamethasone Sodium Phosphate
ITEMS STANDARD RESULTS
Characteristics A White or practically white, odorless, crystalline powder Conforms
Specific rotation +75°~+80° +76°
Purity 98% to 99.9% 99.1%
Identification A. IR Conforms
B. UV Conforms
Chromatographic impurity Total impurities ≤2.0%
Any impurities ≤1.0% conforms
Residue on ignition ≤0.2% conforms
Loss on drying ≤0.5% 0.1%
Organic volatile impurities Meets the requirements conforms
Particle size Micronized conforms
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