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CAS No:223104-29-8 Benzenamine,2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxy-
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SEA0400

  • CAS No.: 223104-29-8
  • Purity: >98%
  • Weight: 371.3773
  • Formula: C21H19 F2 N O3
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:SEA0400
  • CAS No: 223104-29-8
  • Weight: 371.3773
  • Formula: C21H19 F2 N O3
  • Boiling Point: 485°Cat760mmHg
  • Density: 1.254g/cm3

Details

SEA0400SEA0400 is a novel and selective inhibitor of the Na+-Ca2+ exchanger with IC50 of 5-33 nM (inhibiting Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia).

IC50 value: 5-33 nM

Target: NCX

SEA0400, a specific Na+/Ca2+ exchange (NCX) inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease and attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models.

Target:HIV

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CAS No:223104-29-8 Benzenamine,2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxy-

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