AOD-9604,The Fragment is a modified form of amino acids 176-191 of the human (GH) polypeptide. Investigators at Monash University discovered that the fat-reducing effects of GH appear to be controlled by a small region near one end of the GH molecule. This region, which consists of amino acids 176-191, is less than 10% of the total size of the GH molecule and appears to have no effect on growth or insulin resistance.
AOD-9604 works by mimicking the way natural regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified GH. Like GH, the fragment 176-191 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis (the transformation of non-fat food materials into body fat) both in laboratory testing and in animals and humans.