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supply natural Galanthamine Hydrobromide

  • CAS No.: 1953-04-4
  • Purity: 99%
  • Min quantity: 200 Kilograms
  • Weight: 368.27
  • Place of Orign: Changsha ,Hunan,China
Ms.min wang

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Item specifics

  • Product Name.:supply natural Galanthamine Hydrobromide
  • CAS No: 1953-04-4
  • Weight: 368.27
  • Formula: C17H21NO3.HBr;C17H22BrNO3
  • Melting Point: 256 °C
  • Boiling Point: 439.3 ºC at 760 mmHg

Details

Details Description:
Product Name:Galanthamine Hydrobromide
Original Plant:Shorttube Lycoris
Appearance:White to whitish crystal powder
Specification:99%
Synonym(s):Reminyl, Nivalin
Chemical Name:(4aS,6R,8aS)-6-Hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-benzofuro[3a,3,2-e,f][2]benzazepine hydrobromide
Test Method:HPLC
Molecular Formula:C17H21NO3.HBr;C17H22BrNO3
Molecular Weight:368.27
CAS No.:1953-04-4

Pharmacology Action:Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially, Galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.e. neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy.Several trials already showed that Galantamine 16 and 24 mg/day significantly benefits the cognitive, functional, and behavioral symptoms of AD as compared with placebo and proved also to be very effective in symptomatic treatment of senile dementia of Alzheimer's type


Product introduction:
Galanthamine is natural extracted from lycoris radiate,is a tertiary alkaloid derived from snow drop and closely related species. It acts as a reversible competitive acetylcholinesterase (ACHE) inhibitor, while acts weaker on butyrylcholinesterse(BuChE).it is used in the treatment of disorders of the central nerbous system and may be used as an antidote to nonpolarizing muscle relaxants.Galanthamine hydrobromide is a white to almost white powder; sparingly soluble in water; insoluble chloroform,ether and alcohol.
supply natural Galanthamine Hydrobromide

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