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CAS No:1866-39-3 (E)-3-(4-methylphenyl)prop-2-enoic acid
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4-Methylcinnamic Acid

  • CAS No.: 1866-39-3
  • Purity: 99
  • Min quantity: 5000000 Kilograms
  • Price: USD 1~5/Kilograms
  • Place of Orign: wuhan,Hubei,China
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Item specifics

  • Product Name.:4-Methylcinnamic Acid
  • CAS No: 1866-39-3
  • Weight: 162.1852
  • Formula: C10H10O2
  • Melting Point: 198-201 ºC
  • Boiling Point: 300.6 °C at 760 mmHg
  • Density: 1.147 g/cm3

Details

Usage :
It is used to synthesize methyl p-methyl cinnamate. Methyl p-methyl cinnamate is mainly used to synthesize p-bromomethyl cinnamate as the upstream raw material of the antithrombotic drug Ozagrel sodium. P-bromomethylcinnamate is brominated with N-bromosuccinimide to produce p-bromomethylcinnamate. Methyl p-bromomethylcinnamate is in ionic liquid N-n-butylpyridine tetrafluoroborate. After condensing with imidazole at room temperature in the acid salt, alkaline hydrolysis was performed to obtain the antithrombotic drug ozagrel sodium, with a total yield of 67%.

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