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Bortezomib

  • CAS No.: 179324-69-7
  • Purity: >98%
  • Weight: 384.2372
  • Formula: C19H25BN4O4
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:Bortezomib
  • CAS No: 179324-69-7
  • Weight: 384.2372
  • Formula: C19H25BN4O4
  • Melting Point: 122-124°C
  • Density: 1.214

Details

BortezomibBortezomib (PS-341) is a potent 20S proteasome inhibitor with Ki of 0.6 nM.

IC50 value: 0.6 nM (Ki) [1]

Target: 20S proteasome

in vitro: The average growth inhibition of 50% value for Bortezomib across the entire panel of 60 cancer cell lines derived from multiple human tumors from the US National Cancer Institute (NCI) is 7 nM.

Target:HDAC

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CAS No:179324-69-7 [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]<br />amino]butyl]boronic acid

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