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Tadalafil Citrate (Cialis)

  • CAS No.: 171596-29-5
  • Weight: 389.40396
  • Formula: C22H19N3O4
  • Melting Point: 298-300°C
  • Place of Orign: Shanghai,Shanghai,China
Ms.Elaine Lei

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Item specifics

  • Product Name.:Tadalafil Citrate (Cialis)
  • CAS No: 171596-29-5
  • Weight: 389.40396
  • Formula: C22H19N3O4
  • Melting Point: 298-300°C
  • Boiling Point: 679.1ºC at 760 mmHg
  • Density: 1.51 g/cm3

Details

Product Name: Tadalafil Citrate (Cialis)
CAS No.: 171596-29-5
Purity: 99%
Appearance: white crystalline powder
M.F.: C22H19N3O4
M.W: 389.41
Appearance: White crystalline powder
Melting Point: 300°C ~303°C
Loss on drying: NMT 0.5%
Heavy metals(Pb): NMT 20ppm
Residue on ignition: NMT 0.1%
Relative substance: NMT 1.0%
Assay (on dried basis): NLT 98.5%
Standard: USP36
Details:
Tadalafil is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the name Cialis, and under the name Adcirca for the treatment of pulmonary arterial hypertension.
Although sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis) all work by inhibiting PDE5, tadalafil's pharmacologic distinction is its longer half-life (17.50 hours) - compared to sildenafil (4.0-5.0 hours) and vardenafil (4.0-5.0 hours) – resulting in longer duration of action, and so partly responsible for "The Weekend Pill" sobriquet. Furthermore, the longer half-life is the basis for current investigation of tadalafil's daily therapeutic use in relieving pulmonary arterial hypertension. Sildenafil is approved in several world regions as a thrice-daily therapy for pulmonary arterial hypertension.
Tadalafil Citrate (Cialis)

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