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SCR7

  • Purity: >98%
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:SCR7
  • CAS No: 1533426-72-0

Details

SCR7SCR7 is a molecule that inhibits joining of DSBs in cell-free repair system; inhibits NHEJ(nonhomologous end-joining) in a Ligase IV-dependent manner within cells, and activates the intrinsic apoptotic pathway.

IC50 value: ~40 nM in Hela and A549 cell [1]

Target: Ligase IV inhibitor; NHEJ inhibitor

in vitro: SCR7 does not induce DSBs directly to the genome and is Ligase IV dependent.

Target:ROCK kinase

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