Diclofenac Sodium
Latin or English: Diclofenac Sodium
Official name: diclofenac sodium
English Name: Diclofenac, Diclofenac Sodium, Cataflam, Dichronic, Kriplex, VOLTAREN
Commodity name: diclofenac, diclofenac, Armirel M, Divna; Olfen; Arthrotec; diclofenac; kaflan; novolten; day Sony Germany; Antine capsule;
CAS: 15307-79-6
MF: C14H10Cl2NNaO2
MW: 318.13
Specification: 99%
Ingredients: diclofenac sodium 50mg, m entangles the forefront alcohol 200ug
Category: anti-inflammatory analgesic drugs.
Character: White or off white, odorless, easy absorption of crystalline powder tide, the synthesis of this product by inhibiting cyclooxygenase and thereby reduce prostaglandin. Used its sodium salt is colorless crystal, odorless, soluble in water, alcohol and other polar organic solvents and aqueous solution of pH=7.68, pKa=4. The melting point of 283-285 deg. C.
The mechanism of action
1 inhibition of four arachidonic acid cyclooxygenase system, leading to a reduction in prostaglandin and platelet production.
2 inhibition of the oxidase, the enzyme can lead to inhibition of leukotriene generation, especially the dialogue three ene B4 more obvious.
More intake of 3 inhibition of four arachidonic acid release and stimulation of four arachidonic acid.
Representative drug: Divna (also known as Voltaren)
Day Sony Germany; Antine capsule description: This product is enteric coating film, 25mg film is yellow.
Indications of rheumatoid and osteoarthritis, ankylosing spondylitis.
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