Epothilone B
Synonym: EPO906, EpoB, Patupilone, Molecular Formula:C27H41NO6S
Molecular Weight: 507.68
CAS Number:
AppearanceColorless crystals
Purity (HPLC):99.0%
Descriptions:
A compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, epothilone B induces microtubule polymerization and stabilizes microtubules against depolymerization conditions. In addition to promoting tubulin polymerization and stabilization of microtubules, this agent is cytotoxic for cells overexpressing P-glycoprotein, a characteristic that distinguishes it from the taxanes. Epothilone B may cause complete cell-cycle arrest.
Packing: Preserved in tight container 50g /bottle or in demand
storage condition desiccated
protect from light,storage temp.: 20
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