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NVP-TNKS656

  • Purity: >98%
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:NVP-TNKS656
  • CAS No: 1419949-20-4

Details

NVP-TNKS656NVP-TNKS656(TNKS-656) is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.

IC50 value: 6 nM [1]

Target: TNKS2

NVP-TNKS656 was identified as an orally active antagonist of Wnt pathway activity in the MMTV-Wnt1 mouse xenograft model.

Target:Deubiquitinase

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