JNK-IN-8JNK-IN-8 is a selective JNK1/2/3 inhibitor(IC50=4.67/18.7/0.98 nM) that inhibits phosphorylation of c-Jun, a direct substrate of JNK, in cells exposed to submicromolar drug in a manner that depends on covalent modification of the conserved cysteine residue.
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