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Agomelatine

  • CAS No.: 138112-76-2
  • Purity: 99%
  • Min quantity: 1 Kilograms
  • Price: USD 1~100/Kilograms
  • Place of Orign: Wuhan,Hubei,China
Ms.Sunny Lee

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Item specifics

  • Product Name.:Agomelatine
  • CAS No: 138112-76-2
  • Weight: 243.30098
  • Formula: C15H17NO2
  • Melting Point: 107-109°C
  • Boiling Point: 478.8 °C at 760 mmHg
  • Density: 1.109g/cm3

Details

Product Name: AGOMELATINE
Synonyms: AGOMELATINE;n-(2-(7-methoxy-1-naphthalenyl)ethyl)-acetamid;n-(2-(7-methoxy-1-naphthalenyl)ethyl)acetamide;n-(2-(7-methoxynaphth-1-yl)ethyl)acetamide;S20098,N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamide;S 20098;AGOMELATIN;Acetamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)-
CAS: 138112-76-2
MF: C15H17NO2
MW: 243.30098
EINECS:
Product Categories: Aromatics Compounds;Aromatics;Neurochemicals;APIS;API;Agomelatine;Valdoxan, Melitor, Thymanax
Mol File: 138112-76-2.mol
Chemical Properties White Solid
Usage Agomelatine is an antidepressant drug. It is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of
Usage Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively.
Agomelatine

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