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Coluracetam powder

  • CAS No.: 135463-81-9
  • Purity: 99.5%
  • Min quantity: 1 Kilograms
  • Price: USD 1~10000/Kilograms
  • Place of Orign: Wuhan,Hubei,China
Ms.David Lu

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Item specifics

  • Product Name.:Coluracetam powder
  • CAS No: 135463-81-9
  • Weight: 341.40422
  • Formula: C19H23N3O3
  • Boiling Point: 634.1°C at 760 mmHg
  • Density: 1.291g/cm3

Details

Product Name Coluracetam
CAS No. 135463-81-9
Formula C19H23N3O3
Appearance White powder
Purity 99.5%
Package 1Kg/bag
Description Coluracetam (BCI-540) is a nootropic drug of the racetam family.Coluracetam (formerly known as MKC-231) was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California.Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD).BrainCells Inc is currently out-licensing the drug for this purpose.It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.
Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.
Coluracetam powder

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