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Y-27632 (dihydrochloride)

  • Purity: >98%
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:Y-27632 (dihydrochloride)
  • CAS No: 129830-38-2

Details

Y-27632 (dihydrochloride)Y-27632 2Hcl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.

IC50 value: 140 nM (Ki)

Target: ROCK1

in vitro: Y-27632 inhibits ROCK-II while displaying little activity against PKC, cAMP-dependent protein kinase and myosin light-chain kinase (MLCK) with Ki of 26 μM, 25 μM and > 250 μM, respectively, as well as PKA activated by another Rho-family GTPase member, Cdc42.

Target:Antibacterial

Product Links:http://www.medchemexpress.cn/y-27632-dihydrochloride.html

Permanent link:http://www.medchemexpress.com/Y-27632-dihydrochloride.html

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