Product Name:Dextromethorphan Hydrobromide
Product Name Dextromethorphan Hydrobromide
Synonym Dextromethorphan HCL , DXM , Romilar , DM
CAS 125-69-9
MF C18H26BrNO
MW 352.31
EINECS 204-750-1
Assay 98%
Quality Standards USP
Appearance White crystalline powder
Package 1kg/Foil bag
Place of Origin China
Brand Name SMQ
Certification ISO9001, ISO14000, KOSHER
MOQ 100g
Ref. Price USD 0.575/g
Packaging Details 1kg/bag,100g/bag
Delivery Time 1-3 days
Payment Terms T/T, Western union, Money gram
Supply Ability 5000KGS/week
1.OverView:
Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug. It is one of the active ingredients in many over-the-counter cold and cough medicines, including generic labels and store brands, Benylin DM, Mucinex DM, Robitussin, NyQuil, Dimetapp, Vicks, Coricidin, Delsym, TheraFlu, and others. Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.
2.Description:
DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor[4] and a sigma-1 receptor agonist. DXM and its major metabolite, dextrorphan, also acts as an NMDA receptor antagonist at high doses, which produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetics such as ketamine and phencyclidine. As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.
3.Usage:
(1) The primary use of dextromethorphan is as a cough suppressant, for the temporary relief of cough caused by minor throat and bronchial irritation (such as commonly accompanies the flu and common cold), as well as those resulting from inhaled particle irritants.
(2) A combination of dextromethorphan and quinidine, a CYP2D6 inhibitor, has been shown to alleviate symptoms of easy laughing and crying (pseudobulbar affect) in patients with amyotrophic lateral sclerosis and multiple sclerosis. Dextromethorphan is also being investigated as a possible treatment for neuropathic pain and pain associated with fibromyalgia.
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