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CAS No:122111-03-9 Gemcitabine hydrochloride
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Gemcitabine (Hydrochloride)

  • CAS No.: 122111-03-9
  • Purity: >98%
  • Weight: 299.66
  • Formula: C9H11F2N3O4.HCl
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:Gemcitabine (Hydrochloride)
  • CAS No: 122111-03-9
  • Weight: 299.66
  • Formula: C9H11F2N3O4.HCl
  • Melting Point: >250°C dec
  • Boiling Point: 482.7 °C at 760 mmHg
  • Density: ==

Details

Gemcitabine (Hydrochloride)GemcitabineHcl (LY 188011 Hcl) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.

IC50 Value: 50 nM( PANC1); 40 nM(MIAPaCa2); 18 nM(BxPC3 ); 12 nM(Capan2)

Target: Nucleoside antimetabolite/analog

Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP).

Target:CaSR

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