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INT-777

  • Purity: >98%
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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  • Product Name.:INT-777
  • CAS No: 1199796-29-6

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INT-777INT-777(S-EMCA) is a novel potent and selective TGR5 agonist with remarkable in vivo activity (EC50=0.82 uM).

IC50 value: 0.82 uM [1]

Target: TGR5 agonist

INT-777 shows a detergency power similar to CA (4), albeit with slightly lower water solubility.

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Product Links:http://www.medchemexpress.cn/int-777.html

Permanent link:http://www.medchemexpress.com/int-777.html

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INT-747

CAS No: 459789-99-2

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Description: INT-747 INT-747(Obeticholic acid; 6-ECDCA) is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity. IC50 value: 99 nM(EC50) [1] Target: FXR agonist in vitro: The exposure of rat hepatocytes to 1 microM 6-ECDCA caused a...

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