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Trametinib (DMSO solvate)

  • Purity: >98%
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:Trametinib (DMSO solvate)
  • CAS No: 1187431-43-1

Details

Trametinib (DMSO solvate)Trametinib (GSK1120212; JTP 74057) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2.

IC50 value: 0.92 nM/1.8 nM (MEK1/2) [1]

Target: MEK1/2

in vitro: GSK1120212 inhibits the phosphorylation of MBP regardless of the isotype of Raf and MEK, with IC50 ranging from 0.92 nM to 3.4 nM.

Target:Wee1

Product Links:http://www.medchemexpress.cn/trametinib-dmso-solvate.html

Permanent link:http://www.medchemexpress.com/trametinib-dmso-solvate.html

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Trametinib

CAS No: 871700-17-3

Purity: >98%

Min quantity: null null

Price: null ~ null null

Description: Trametinib Trametinib (GSK1120212; JTP 74057) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. IC50 value: 0.92 nM/1.8 nM (MEK1/2) [1] Target: MEK1/2 in vitr...

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