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AZD-6482(S)

  • Purity: 98%
  • Price: USD 300~2000/Kilograms
  • Place of Orign: wuhan,Hubei,China
Ms.Luna Wang

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Item specifics

  • Product Name.:AZD-6482(S)
  • CAS No: 1173900-37-2

Details

AZD6482 is a potent, selective and ATP competitive PI3K inhibitor (IC(50) 0.01 μm). AZD6482 inhibited insulin-induced human adipocyte glucose uptake in vitro (IC(50) of 4.4 μm). This is the first human target validation for PI3K inhibition as anti-platelet therapy showing a mild and generalized antiplatelet effect attenuating but not completely inhibiting multiple signaling pathways with an impressive separation towards primary hemostasis. AZD6482 at 'supratherapeutic' plasma concentrations may attenuate insulin signaling, most likely through PI3K inhibition.
AZD-6482(S)

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AZD-6482(R)

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Purity: 98%

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Description: AZD6482 is a PI3K inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3K than PI3K, PI3K and PI3K. Phase 1.

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AZD1152-HQPA

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