Dolutegravir is a two-metal-binding HIV-1 integrase inhibitor with IC50 of 2.7 nM, with modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. It blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI).https://www.bocsci.com/dolutegravir-gsk1349572-cas-1051375-16-6-item-438457.html
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Business Type: Manufacturer
Product/Service (We Buy): 101 - 500 People
Year Established: 2005
Number of Employees: 101 - 500 People
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