TacrolimusTacrolimus(FK506; FR900506) is a potent immunosuppressive drug often administered to transplant recipient patients and exhibits a variety of adverse cardiovascular effects.
IC50 Value: 0.47 nM (Inhibition of lymphocyte proliferation) [1]
Target:
in vitro: MP and tacrolimus decreased the number of circulating helper-T cells with IC50 values of 23 ng/ml for MP and 6.7 ng/ml for tacrolimus.
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