AZ505AZ505 is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=0.12 uM) with potential anticancer activity, >600 fold than SMYD3(IC50>83.3 uM); DOT1L(IC50>83.3 uM);EZH2(IC50>83.3 uM).
IC50 Value: 0.12 uM [1]
Target: SYMD2
The kinetics of AZ505 binding to SMYD2 were determined by inhibition kinetic experiments using ?lter binding assays.
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