Product Name: 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide
Synonyms: LABOTEST-BB LT00244861;GLYBENCLAMIDE;GLYBENZCYCLAMIDE;GLYBURIDE;GIBENCLAMIDE;GLIBENCLAMIDE;5-CHLORO-N-[4-(CYCLOHEXYLUREIDOSULFONYL)PHENETHYL]-2-METHOXYBENZAMIDE;5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)CARBONYL]AMINO]-SULFONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE
CAS: 10238-21-8
MF: C23H28ClN3O5S
MW: 494
EINECS: 233-570-6
Chemical Properties White Crystalline Powder
Usage antihyperglycemic
Usage Glyburide is a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic.
Biological Activity ATP-dependent K + channel (K ATP ) and CFTR Cl - channel blocker. Inhibits K ATP currents in the pancreas, causing an increase in intracellular Ca 2+ and insulin secretion. Inhibits recombinant CFTR Cl- channels with an IC 50 of 20 μ M.
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Permanent link: http://www.vvchem.com/sell/cas:10238-21-8,3287268.html
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