Tegobuvir is a novel imidazopyridine inhibitor of hepatitis C virus (HCV) RNA replication in vitro and has demonstrated potent antiviral activity in patients chronically infected with genotype 1 (GT1) HCV. Tegobuvir exhibits reduced activity against GT2a (JFH1) subgenomic replicons and GT2a (J6/JFH1) infectious virus, suggesting that the compd.'s mechanism of action involves a genotype-specific viral component.
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United States![CAS No:1000787-75-6 5-[[6-[2,<br />4-bis(trifluoromethyl)phenyl]pyridazin-3-yl]methyl]-2-(2-fluorophenyl)<br />imidazo[4,5-c]pyridine](/structure/cas-100/1000787-75-6.png)